i have a light bike, a lighter bike and a heavy bike. the light bike (fixed) gets me from point a to b the fastest by far. the heavy bike (also fixed, same ratio), the slowest. this could have something to do with the components and the geometry, but it "feels" heavier when i ride it. it's also a bigger pain in the ass to hang up when i get home.
I also have a harder time sprinting up steeper climbs with it, but it could have something to do with it having risers vs. bullhorns on my other bikes. i almost always end up out of saddle on the larger hills north west of philly when i ride it.