Very good questions...sorry, I should have addressed them originally. I wear size 10 1/2 in street shoes, size 45 in Shimano cycling shoes, and size 11 in the Zoots as well as the Newtons...the fit is very similar. I previously wore Brooks in size 11 1/2.
I hope that helps.
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Fredo, you're my older brother and I love you...but don't ever take sides, with anyone, against the family again...ever.