I used Sheldon Brown's cold-set method to re-space the rear of a Burley Zydeco to 130mm so I could put on Mavic Ksyreium Elites I had lying around. Wouldn't have done it if we were over 250lbs, wheelset had a rider weight limit and the frameset was not chromoly. I had to adjust the rear derailleur hanger and front derailleur angle to get it to shift properly. Did a MS 150 recently on it and it was smooth ride. I surprised my self that it worked out so well. That's my experience on the subject.