If I understand your post correctly...

1) Neutral
2) No

If you have horizontal or semi-horizontal dropouts, then you don't have to worry about how far back the wheel is (further away) from the bicycle. If it's too far back, it certainly isn't going to fall out (as they bend back around). I would be more concerned with it being too close to the start of the dropouts. If it really bothers you how far back they are, cut out two links from the chain. As long as you have a tight chain, I wouldn't worry about it. If the chain is long enough where you're as far back in the dropouts as possible, and still have slack, cut it.