Originally Posted by DannoXYZ

The only time 3x plays a factor is in torsional strength. Vertical and lateral strength is identical regardless of the number of crosses (really tangential angle), and is based purely on numbers of spokes and tension. Due to the torque-reduction through the gearing, a human generates a miniscule amount of torque at the hub. So little in fact, you actually get minimal wind-up even with an all-radial rear wheel.