I second Berninas if you get a non-industrial machine (which I know nothing about). I have a great Bernina and it's awesome. I make bags, too, not outdoor or messenger bags with heavy canvas or Cordura, but I frequently sew through lots of layers, heavy interfacing, nylon webbing, etc.
But I would still lean towards an industrial machine. My Bernina can handle heavy stuff, but it's not designed for it. Get the right machine for the job.