Case
Yes to rear wheel removal, yes to RD removal, yes to all other removals people generally make when packing their folders.
Though the case is soft, I got some sheets of hardboard and reinforced all the surfaces on the inside.....helps with any pointed/concentrated impacts......adds to weight, though it is easily removable if weight matters.
I also fabricated cheap spacers like BF sells that go through the complete bike when packed, to keep the suitcase sides well spaced. Made them out of PVC pipe, plumbing fixtures, hardboard, and epoxy......they work well, they're much more substantial than the BF model.