my view on it is unless your either
a) at a very high level of fitness, where its difficult to get stronger/lighter without massive amounts of working out
b) just like having things for the "gee whiz" factor
then saving 50grams isnt worth the extra 20-100% markup on the part.
Sometimes lightweight happens...if so then great! I wouldn't obsess about it though, well unless your riding a 35-40lb roadie (if such a beast exists)..then you could possibly give it a little nip and tuck