Here is the route that should work for you from Weirton,WV to Richmond,IN from the Montour Run Trail you can catch the Panhandle trail all the way into Weirton. I've ridden the section from the Montour Run Trail to Morristown, OH and the sections from Cambridge, OH to Richmond, IN (except downtown Columbus). I've driven the rest many time in a car.
The only sketchy parts of this route are about 5 miles of Rt. 2 in West Virginia and the city part of Columbus. I think you could work out a route through Columbus on one of the commuting forums.
http://maps.google.com/maps?f=d&sadd...99&ie=UTF8&z=8
Let me know if you have any questions or comments.
monkd