Ind. Fab is great - I've seen some of their bikes. Steelman in NoCal makes great bikes, too, if you don't mind powdercoating. I recently had my Surly CrossCheck (not a custom frame) retro-fitted with S&S Machine BTC's (
www.sandsmachine.com) by Stephen Bilenky at Bilenky Cycle Works. He did an amazing job. He builds awesome custom bikes. He can make any style frame with almost any tubeset - or even combinations of various tubesets, depending on what's best for you. If you travel with your bike, S&S couplers are the only way to fly!