There seems to be a general agreement that folding bikes are more practical and more fun to ride. Lots of people including me have ditched their large-wheeled bikes. Despite the general views that small wheels are slow, harsh and prone to get stuck in pot-holes, IMHO these views are wrong or at least poorly understood. Small wheels offer significant advantages and almost no disadvantages.
Folding bikes are usually heavier due to heavier frames and low quality components; but can often be made significantly lighter by selecting lightweight quality components.
So yes you can go ahead and get rid of your hybrid if you want to and use the folding bike exclusively.