Been doing it for years on many different bikes, wheels, tires. I do it on my 20" wheeled folder, my daughter's 24" bike, mountain bikes, and 700c. It isn't supernatural. It just takes practice. Once you get good at it, it is a big time saver. That said, I will admit that brand new wire bead tires are the hardest; bad the wire quickly strecthes and it gets easier. Kevlar beads are easier new, but dont stretch over time.