I prefer tires with reflective sidewalls, no unbalancing, less dorky looking, and they don't seem to affected by getting wet. The reflective sidewalls seem to have a larger angular range over which they are effective and a much larger total surface area than the standard spoke reflectors, I witnessed this a few months ago seeing two bikes crossing the road head of me on with spoke reflectors only, and the other with reflex tires, the difference was startling, they should be mandatory on all new cycle tires. As to the problem of moisture and reflex tapes, the vehicular grade reflective tapes have a smooth finish which encapsulates the reflective material and are largely unaffected by moisture, the tape that lose their reflectivity tend to be the sew on types for clothing etc. which don't encapsulate the reflectors.