Gel gloves.

The gel pads that go under the bar tape. (really nice)

Padded bar tape.

softer tires.

A heavier bike makes the tires take more of the bumps instead of you.

Raising the bar reduces pressure on the hands.

Tipping your seat back a little reduces pressure on the hands.

Take your best pain meds an hour before riding, and right on time, if it's a long ride. If you need reminders set the alarms on your cell phone as a timer.

Some people do better with one very long ride, then two days off to let the joints fully recover.