I rocked 46/17 for a while, loved it but wanted more work/speed, so I put a 15T on the back and have had a couple of weeks on that and really love it. I like that I can't spin out and can just feed it to her [the bike] until I tire from strength rather than being out-spun.
When the snow comes down and stays, I'll probably pop a 17 on the back again or just switch to a 42 ring and run the 15. I ran 42/17 last winter with great results.