I am 6'1.5" with relatively long 35.5" inseam. I ride a '85 Trek 760 frame with 60cm st, 58cm tt, and a 90mm stem with about 3" of saddle to bar drop. I set it up according to the fit chapter in Greg Lemonds '86 book. My previous bike was a '72 58cmst/58cmtt Masi with a 110mm stem, 4" of drop and a much more relaxed seat tube angle. Both quill stems are at max extension. I ended up having a 3" shorter cockpit on my 60cm frame than the 58cm. I love the new bike as I can keep my elbows quite bent (30-60 degrees) in the drops to get low without any lower back strain. I can also run deeper drops so I have more variety between my hand positions. I shake my head when I pass folks riding such aggressive positions that they have to keep their elbows locked because they have so much weight on their hands from being too hunched over and stretched out. A fast position is a comfortable position.
So IMHO, go for a shorter top tube while maintaining a reasonable saddle to handlebar drop. That way you can have more choices in stem/handlebar combos. Also, check out frames with steeper seat tube angles so that you don't get ridiculously stretched out when you jack your seat up. Zero setback seatposts also help with this.