I may sound like a total poseur, but I sometimes do plan some of my common loops according to the wind. Obviously, there is no way to avoid it, but I will sometimes plan it so that I finish with the wind - it's fun to have a boost towards the end after you've been working against the wind ... get the worst over first, etc.
Sometimes I plan so I'm in more sheltered areas when going against the wind to reduce the effect a little.
Sometimes I (here's the poseur part) plan so I'm going with the wind in the stretches I'm most visible to traffic so as to think I'm lookin' good to the onlookers (not likely though - I'm in my 50s and have chicken legs).
I know, I know, embrace the wind, it will make you stronger. But at my age, I'm not a racer and just ride for fun and fitness, mostly fun. Plus there are a good plenty of tough hills on every single ride I do, so I get plenty of difficulty, thank you very much.
I take a look at a flag that's visible from my office parking lot during my noon rides, and sometimes plan accordingly. There are several loops I can choose ranging from about 12 miles to 35 and more. Other times I just don't give a crap either way.