Originally Posted by
jccaclimber
You can do it. However, you want to watch out for your computer face if you have one and your brifter hoods if you are on pavement. Other than some scratches on those items you should be fine.
Personally, I usually prefer to take the wheel out while the bike is upright and either a) have someone else hold it or b) put it down on its left side.
I also scratched the top of the headlight when I forgot to rotate the headlight before inverting the bike-so that's less of an issue if you invert on grass but with increased concern on dirt contamination. I usually invert for rear repair because it's so much easier to get everything back in place and properly aligned, but a front is so trivial to get back I rarely invert.