The big one for me is getting some new wheels, on order now- Easton EA 90 SL's. I should have them in February some time.

Also upgraded this winter:
Crankset (FSA energy)
Ultegra SL Rear Der.
Ultegra 11-23 cassette (for the Eastons)
Easton EA 90 stem
Ultegra SL calipers
Selle Italia SLR saddle
tires- Conti 4000's
lightweight tubes

Dropped about 2 pounds off the bike to bring 16.5-17 lb range
That is all. That is enough.