I should have been more specific in my needs. I'm looking at building up a single speed commuter on 700cc wheels. This will be my "bomb-proof", everyday ride. I'm mostly on pavement, but would like to be able to handle mud/dirt occasionally. Hopping curbs and bad pavement are a daily occurance on my route, so I want a nice big tire for a softer ride. I'm aware that I'll have some extra rolling resistance to contend with and that doesn't bother me.

The bike I'm looking at is the Fantomcross Uno. It can take a 29 inch wheel, so maybe that it the route I should take?