So I installed a new shimano M443 crankset into a Miyata triple-cross frame, but the crank arms don't seem to be centered. The left arm is about 1/4" closer to the chainstay than the right arm. The frame was checked with an alignment tool and it isn't bent.

The bottom bracket that was included with the crankset was Shimano's ES25 octalink, for E-type derailers (68x121). It came with a 2.5mm spacer that I placed on the drive-side threads in place of the E-type hanger that wouldn't be present (I assumed this was what the spacer was for).

My question is, is this large of a difference in clearances normal? Should the spacer go on the left side? My caad9-5's crankset is perfectly centered, but my roommate's trek 7.2fx is offset about 1/8" in the opposite direction.