I just installed a Wippermann 10S1 chain on my Cervelo R3, which has FSA crank, ultegra cassette and Dura-Ace 7800 derailleur. It runs and shifts ok on the small chain ring. When I put it on the big ring, its noisy as heck when I use any of the four largest gears on the rear cassette. The noise is loud enough to be totally unacceptable. I suspect this is not normal behavior. I did note that the chain is pretty tight on side to side play compared to the dura-ace chain I pulled off there (which had 1600 miles and minimal wear).

Any thoughts or similar experience?

Bob