Adjust the fit, so that more of the weight is on your seat/legs vs. your hands.

There are a variety of factors in play here, so some of the options are:
1. Get a properly sized frame and then build that one up appropriately. This is the most expensive, but best option.

2. Adjust the seat angle. If it's angled too far forward, you'll be putting your weight on your wrists, so angling it back and making it flatter might help. (This is free, but the downside is that if your bars are too low, and you're not very flexible, a less angled seat may mean you're putting too much weight on the horn of your saddle which gets very uncomfortable very fast.)

3. Adjust the handlebar height. a) Get a set of handlebars with a higher rise. b) If you've got a threaded fork, raise the stem / replace the stem. If you've got a threadless fork, get a steering tube extender and mount your handlebars on that, and maybe get a shorter stem as well.

4. As the previous poster said, vary your position in and out on your Oury's. Sometimes an inch or two of range helps make things more comfortable.

You can also play with seat height/fore-aft position, but those are the major items to getting your bike fitting properly.

Good luck!