I would simply state that I find the limited advantagers in some circumstances of larger wheels beyound 20" are not great enought to justify a bike that is not multi- modual transportable. I found that my 20" downtube set up as a roadie was quick enought to make buying a road bike unnessary.
JUdging from my experience ,and the Moulton evidence , for road use it least, the debate of wheel size is only worthwhile for competitive cycling. Other than than its a matter of market forces and personel preference.
As for a mountian biking I feel a simular experience would occur with a 20" wheel specialist bike or a converted BMX bike that could fit in to cars easier.
How do FS downtube owners or jetstream owners find the bikes compaire for non preformance riding compaired to their mountian bikes ?