I'm about 105, probably 112 with backpack and tools. I ride mostly cross country, like to do big climbs with long downhills. Usually start with firm tires (~35 lbs.) and the rear shock between 100 and 150 (no lockout), then let everything exhale for the downhill run. Probably run 20 lbs. or less in the tires going downhill, they have to be really soft at my weight or I can't get traction for braking and turns. Cannondale Jeckyl, FS, 26 X 2.25's on it now.