I'd pay $250+ for a saddle if it provided me comfort each and every ride. So far, the only saddle that I've found that comes close to this is a $50 Bontrager inform R. I shelled out $135 for the Bontrager RXL and hated it. Tried the cheaper R and it was like I went from a 2x4 to a couch.
Sure, I'm paying the slight price in weight, but I don't care how light or heavy something is as long as it is comfortable.