The lower your saddle, the more your kneecaps are compressed into your femurs which stresses the cartilage surfaces on both your kneecaps and femurs.
If you do have patellofemoral syndrome then the last thing you want is having your saddle too low.
I had a patellofemoral flare-up last summer and I rechecked my fit on the bike, only to find that my saddle was lower than the fitter had prescribed. I set it back at his prescribed height at 79cm and felt like I had lost some leverage but I got used to it so hopefully you can adjust, too.