It took 13 posts for the "Recumbent" answer to show up. That is because we're too busy riding to be on the computer! We can ride for ever without hand numbness and/or hand pain issues.

JanMM is spot on though. If all else fails, recumbents are worth a try. Since I've switched I've been logging more miles than I ever dreamed would be possible, all of them pain free. My only constraint now is time.