I don't have a knee stress measuring device. Does anyone? How could you possibly know what's going on inside your knee joint with slightly altered saddle positions? I say that most responses are pure conjecture.

FWIW, I've tried everything from 1cm forward to 3cm back (of KOP). I do a lot of climbing and feel that 1-2cm back works best for me, but the larger benefit is reduced weight on your hands and the ability to comfortably tolerate a larger saddle to bar drop. I don't even bother to check KOP these days, since I feel that weight balance is more important. Even the experts don't agree on how to check KOP. Andy Pruitt uses the very front of the knee to the end of the crankarm, while others say to use the lower boney protrusion to the pedal spindle.

A lot of posters on this forum make the mistake of using a nonsetback post that places too much weight on the hands. Then they use a short stem and little saddle to bar drop to cure the discomfort created by the first mistake. The result is an upright Fred fit.