Hey, lungdoc.
Out of curiosity, is it possible for someone to be unreactive to the methacoline/histamine challenge yet still experience reduced lung capacity when exposed to cold, dry air?
I've never had a problem with reduced lung capacity other than when exercising in cold air. One would think that since I live in the Atlanta area (insanely high pollen counts, high ozone levels, the works) that something else would set it off if I had asthma.