Been riding the SPD-SL pedals for a while now with the yellow cleats and DA PD-7800 pedals. The cleats are pretty much centered on the bottom sole bolt pattern.
I love them but can't whipskid in an emergency because as I rotate my foot to whip the bike I clip out sometimes to the right. I have to stick with regular skids to stop. I've been meaning to try tightening up the spring screw but I like having it loose in case I have a spill.
Bottom line is I love 'em and am not going back to straps. Don't really care too much about wearing bike shoes, I'd just rather throw a pair of sandals in my bag.