If you mean removing the rear wheel I tend to disagree. The Rohloff hub with QR is a toolless removal. All my other IGHs require one 15mm open end or box wrench.

The Nuvinci if installed in a bike frame with vertical dropouts requires the 15mm wrench, a 22mm wrench and a hex key. The VDO adapter kit uses a anti rotation plate on the drive side that also bolts to the derailleur mount, under the chain tensioner. This requires removal of the tensioner to remove the wheel.

This is the reason I recommend use of the Nuvinci hub primarily on bikes with horizontal dropouts. The Nuvinci chain tensioner and VDO kit make wheel removal a PITA out on the road.