I assume it's a machine-built whee? Have you taken it to a good shop to have a good wheelman give it a once-over? A good builder makes all the difference in the world. My old rear wheel is a Deep V w/ a formula track hub, and it has been fantastically durable, but it's built up with butted spokes and was done by John Dacey at Business Cycles (and that guy builds a mean wheel).