You said 4 stars. Assume you know what that costs in downtown Seattle.
Some choices:
- Hotel 1000
- Hotel DECA
- Inn at the Market
- W Hotel
- Hotel Andra
- Hotel Monaco
- Alaska Club
- Pan Pacific
- Four Seasons
etc.
If I were in town for the weekend I'd choose the Belltown area. If it's raining, I'd rather not be at the Edgewater or Marriott because you'd have to walk several blocks to get to bars/restaurants. The Hotel Andra, for example, gets you right in the middle of the action.