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Semaglutide/Ozempic anyone?

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Semaglutide/Ozempic anyone?

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Old 06-28-23, 06:01 AM
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I started on this at the end of May. My provider gave tons of information on it at the initial consultation. Started at the .25 dose, had zero issyes. Did take a prescribed anti-nausea med, as recommended, but quickly found I didn't need it. Two full weeks on introductory dose, no real changes other than slight appetite reduction. Moved to .5 dose, a bit lower appetite, total of 10lbs +/- a couple since the start. Clothes fit better. Low carb was recommended, and I've never had much issue with that, in fact I always preferred that type of regimen. However I am having issues with reduced energy for biking sometimes, especially if there's an added "difficulty factor" like heat/humidity (I purely detest Temps over 75, especially when it's damp too)
Anyone else doing this have energy probs?
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Old 06-28-23, 06:57 AM
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Originally Posted by exercion
Anyone else doing this have energy probs?
Usually only for the day or two after injection.

I end up sleeping almost all day the day after injection, and the next day I'm still tired, but not quite as bad.

My wife has the same reaction after injection - sleeps all day the day after, and is tired the second day.
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Old 06-28-23, 03:52 PM
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My doctor prescribed it, but it's on backorder, which is annoying on a "First World problem" scale, but in reality, is what it is.

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Old 06-28-23, 05:48 PM
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Originally Posted by exercion
Anyone else doing this have energy probs?
I still have energy problems over four months after I started.

Reduce your calories drastically and that’s what happens I guess. I am at about 46 pounds down and my body is violently fighting trying to keep me from hitting 50

doesn’t help that I took a temporary work assignment 600 miles away from home. I was stressed about it leading up to the assignment and two weeks into the gig and I’m still stressed and not eating properly

i brought my e bike with me and know if I buckle down and eat in a strict fashion and get the bike out it will happen, but I can’t tell you how much of a shock it was going into an office environment working out of a cubicle.
Everyone is super nice, but every other day, someone sends us a cake, brings donuts, after work cocktails and dinners. It’s social and that’s nice —- and yes, I do have the final say on what goes in my mouth but it’s like taking a rooster into the henhouse.
Yesterday was free food trucks and beers (limit 2- honor system- it’s an insurance company after all) outside on the company lawn

50 is a important way point for me, but it’s not the end goal. I should have cruised past it 2 weeks ago
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Old 06-29-23, 06:35 AM
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Originally Posted by DMC707
I still have energy problems over four months after I started.

Reduce your calories drastically and that’s what happens I guess. I am at about 46 pounds down and my body is violently fighting trying to keep me from hitting 50
I seem to have plateaued at 40 lbs down. I keep gaining/losing the same 1-2 lbs over the last three weeks. This morning I did finally drop down below 270, so that's a good sign.

Originally Posted by DMC707
doesn’t help that I took a temporary work assignment 600 miles away from home. I was stressed about it leading up to the assignment and two weeks into the gig and I’m still stressed and not eating properly

i brought my e bike with me and know if I buckle down and eat in a strict fashion and get the bike out it will happen, but I can’t tell you how much of a shock it was going into an office environment working out of a cubicle.
Everyone is super nice, but every other day, someone sends us a cake, brings donuts, after work cocktails and dinners. It’s social and that’s nice —- and yes, I do have the final say on what goes in my mouth but it’s like taking a rooster into the henhouse.
Yesterday was free food trucks and beers (limit 2- honor system- it’s an insurance company after all) outside on the company lawn

50 is a important way point for me, but it’s not the end goal. I should have cruised past it 2 weeks ago
About 7 years ago I was on the Naturally Slim program. It mainly taught good eating habits - portion control, eating slowly, only eating when hungry, etc. I lost quite a bit of weight on it. Then my job changed and I went from a situation where I had full control over when/if I took breaks to being forced to go to lunch at the same time every day, whether I was hungry or not. I knew that just because it was a "lunch" break, it didn't mean I was required to eat. I knew I could go for a walk, or read a book, or whatever. But I found that I was hungry. So I ate. Then portion control went out the window due to not wanting to waste food. Add to that the fact that the shop I was in was really big on feeding us once or twice a week. So I started to gain the weight back. On the bright side, it took 2-3x longer to gain the weight back as it did to lose it.
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Old 07-03-23, 09:49 AM
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I'm down a net 22 lbs. since March 17th but, due to having started heavy weight training at the same time, I have also gained 13 lbs. of lean muscle. This being said, I have removed a total of 35 lbs. of actual fat according to the body comp machine at the clinic I go to. The clinic prescribed semaglutide mixed with B1 from a local compounding pharmacy (don't hate because it's not the Wegovy brand). I still have to consciously watch what I eat but this truly gives me a fighting chance.
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Old 07-03-23, 04:33 PM
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Studies have found that people do lose a lot of weight with the semaglutide drugs but regain it in a few months if they stop taking the drug. At $12,000 a year for life I do not see this as a viable solution for most people. I understand the desire to have a pill or a shot and no expend wny effort and lose weight but it is by far the most expensive route to take.

The alternative is prolonged exercise which is not possible for some individuals. For those who can exercise they are going to get more long term benefits from doing so.
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Old 07-06-23, 02:49 PM
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Originally Posted by Calsun
Studies have found that people do lose a lot of weight with the semaglutide drugs but regain it in a few months if they stop taking the drug. At $12,000 a year for life I do not see this as a viable solution for most people. I understand the desire to have a pill or a shot and no expend wny effort and lose weight but it is by far the most expensive route to take.

The alternative is prolonged exercise which is not possible for some individuals. For those who can exercise they are going to get more long term benefits from doing so.
Thanks for the encouragement. I can't express just how grateful I am for your words.....mainly because Mom doesn't like me using that kind of language.
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Old 07-06-23, 03:29 PM
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Originally Posted by exercion
Thanks for the encouragement. I can't express just how grateful I am for your words.....mainly because Mom doesn't like me using that kind of language.
Rejection of the truth doesn't make it any less the truth.
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Old 07-07-23, 08:27 AM
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Originally Posted by Leisesturm
Rejection of the truth doesn't make it any less the truth.
And assuming that one person's path is the only "truth" for everyone, regardless of anyone else's situation is arrogant and unhelpful at best. Jumping into a thread where people are discussing their experiences, good bad and indifferent along a common path the way it was done is just being an a#$hat. YMMV.
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Old 07-10-23, 07:28 AM
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Originally Posted by Calsun
Studies have found that people do lose a lot of weight with the semaglutide drugs but regain it in a few months if they stop taking the drug. At $12,000 a year for life I do not see this as a viable solution for most people. I understand the desire to have a pill or a shot and no expend wny effort and lose weight but it is by far the most expensive route to take.

The alternative is prolonged exercise which is not possible for some individuals. For those who can exercise they are going to get more long term benefits from doing so.
I completely understand the limitations & drawbacks to using it.

I view it as a tool to help me lose the bulk of the excess weight I have, and help to renew the use of good eating habits (portion control, meal frequency, etc.). If/when I do go off of it, I hope to have the proper habits in place to maintain whatever weight I am then at without the need of the medication.

As for the cost over time, eventually the price will come down. The main manufacturers are also currently working on a pill form that should be cheaper to produce.
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Old 07-10-23, 10:18 AM
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Originally Posted by monogodo
I completely understand the limitations & drawbacks to using it.

I view it as a tool to help me lose the bulk of the excess weight I have, and help to renew the use of good eating habits (portion control, meal frequency, etc.). If/when I do go off of it, I hope to have the proper habits in place to maintain whatever weight I am then at without the need of the medication.

As for the cost over time, eventually the price will come down. The main manufacturers are also currently working on a pill form that should be cheaper to produce.
I'm sorry, I must quibble with your use of the phrase: "I completely understand the limitations and drawbacks to using [it]. I'm sure you think you do, but, even in these early days, the number of people running hard into the wall of reality shows how badly most users want to believe they are the ones that are going to succeed where others fail. Vaping is another scam foisted on the vulnerable that promises the gift of time to get ones house in order but just becomes another expensive habit and the revenue continues to flow to you know where. By the very fact that you mentioned common sense steps to weight reduction you also rebuke the claim that you need any time to implement those strategies. I don't know of a health plan in the world that pays 100% of a drugs cost. I don't know what the co-pay is for these drugs but I'm pretty sure they would cover enrollment in a prepared meal plan like factor75.com.
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Old 07-10-23, 10:36 AM
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Originally Posted by Leisesturm
I don't know of a health plan in the world that pays 100% of a drugs cost.
My wife's health plan through the Cherokee Nation covers 100% of all medications, as well as all office visit copays. She only has to pay the monthly premium for the plan ($205.23/month). Consider yourself educated.
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Old 07-10-23, 10:43 AM
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Originally Posted by Leisesturm
By the very fact that you mentioned common sense steps to weight reduction you also rebuke the claim that you need any time to implement those strategies.
Because there is more to weight loss than just "common sense steps". There can be psychological issues to overcome, as well as physical issues. And sometimes both combined can be nearly insurmountable without some sort of outside help. My grandparents lived through the Great Depression, and passed on their frugality traits to my dad, who then did his best to ingrain them in me. It is extremely difficult to fight decades of conditioning to not waste food when eating. Being on Mounjaro helps, because I'm just not physically able to eat as much, so I order/make smaller meals. Even then, I may not eat all of it, but I still feel guilt over wasting the small amount that doesn't get eaten. But wasting it is a much better alternative than vomiting it up the next morning. Without the medication, there'd be no repercussions to overeating, other than gaining/not losing weight.
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Old 08-02-23, 10:17 PM
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I’ll be at the 6 month mark in a few days and have hit 62 lbs down. The bottle of 2013 Dom Perignon I bought for myself to celebrate 50 remains unopened as I was out of town when I hit it. So it will now be the 75 pound celebration bottle

im okay with these results so far. Someone said

”just lose the weight. The chances of regaining it are statistically very similar whether one loses it rapidly or takes a slow approach. We’re not guaranteed a tomorrow so just get it off and get to enjoying your life”

pretty simplistic but there is wisdom there and this was the first thought in my head when I started this
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Old 08-07-23, 10:22 AM
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I started Wegovy in January. My starting weight was 285 lbs. At my last weigh in, I was at 210 lbs. Overall I’m feeling great. I’m eating well, and getting lots of exercise.
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Old 08-09-23, 06:35 AM
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https://gizmodo.com/obesity-drug-weg...dea-1850716907
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Old 08-09-23, 07:34 AM
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I saw that on the news this morning. It still needs to be independently verified.

I also saw that Wegovy is being investigated for causing stomach paralysis in some patients.
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Old 08-18-23, 02:14 PM
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I'm going to read this with a lot of interest !

My standard weight was around 165 pounds. Work stress and children stress made me climb to 232 in 20 years.
Eating like a rat in a cage, plus too much beer ... Since 3 months, I stopped alcoholic bevereages, my appetite was immediately reduced. I'm loosing approximately a pound a week. I also try to bike regularly. I'm still craving for a good beer almost every evening and its extremely painful...
I perfectly understand that going down from 300 + is superhuman.
Unfortunately humans are genetically engineerd to store as much calorie as available.

Here in France GLP 1 agonists are officially only available for severe diabete.
Seeing how overweight is dangerous, those drugs are probably a good thing.
Loosing weight reduces so many risks : cardio-vasular, osteo-articular, sleep apnea, diabete ...
The main known side effects are nausea due to a slowing stomach and a rebound of weight at the end of the treatment.

It's a new problem for people undergoing surgery : it's really important for the anesthesist to be aware that one take Ozempic, there's a real risk of "inhalation" ie vomiting in the respiratory tract, which is really life threatening.

As for the price... Pharamceutical labs tends to calculate on avoided risks : for instance a drug "replacing" the need of a liver transplant will cost the price of the surgery including every possible incident. Industrially making these products is generally relatively cheap.R&D is where most of the cost is.

By the way Novo Nordisk is a danish brand
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Old 08-18-23, 05:02 PM
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A recent study with randomized 1961 adults conducted over a 68 week period found that once people stopped taking the drugs they regained two-thirds of their original weight within one year.

Study summary:"In conclusion, among adults with overweight/obesity, after a substantial reduction in body weight during 68 weeks of treatment with once-weekly s.c. semaglutide plus lifestyle intervention, subsequent treatment withdrawal led to most of the weight loss being regained within 1 year, and a similar change in some cardiometabolic variables back to baseline, reinforcing the need for continued treatment to maintain weight loss and cardiometabolic benefits."
Seldom mentioned is that people taking these drugs lose body muscle and have a lower resting metabolism and also experience significant bone loss (similar to the effect of a keto or similar high protein diet).
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Old 08-21-23, 06:13 PM
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Down 40 lbs. of Fat and Up 14 lbs. of Muscle

Started 290 lbs. back in early February. The clinic that I go to has a InBody body composition scanner that I can use any time I want to. It shows (with a printout of metrics) that I am losing fat and gaining muscle. I lost 5 inches off of my waist. Now... I have made serious lifestyle changes. I vigorously lift weights 4 to 5 hours per week and ride 3 to 5 hours per week. I prioritize protein in every meal, take supplements to include "green powders' such as AG1 and make a conscious effort to get enough sleep. I get my Semaglutide from a compounding pharmacy and thus do not pay the exorbitant prices for the name brand Wegovy.

Haters gonna hate but I am willing to stay on some level of Semaglutide for the rest of my life if I have to. It has given me a fighting chance to get my health back. Anyone who doesn't understand this has never spent most of their life contending with obesity.
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Old 08-24-23, 07:03 AM
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Originally Posted by Grudey1
Started 290 lbs. back in early February. The clinic that I go to has a InBody body composition scanner that I can use any time I want to. It shows (with a printout of metrics) that I am losing fat and gaining muscle. I lost 5 inches off of my waist. Now... I have made serious lifestyle changes. I vigorously lift weights 4 to 5 hours per week and ride 3 to 5 hours per week. I prioritize protein in every meal, take supplements to include "green powders' such as AG1 and make a conscious effort to get enough sleep. I get my Semaglutide from a compounding pharmacy and thus do not pay the exorbitant prices for the name brand Wegovy.

Haters gonna hate but I am willing to stay on some level of Semaglutide for the rest of my life if I have to. It has given me a fighting chance to get my health back. Anyone who doesn't understand this has never spent most of their life contending with obesity.
Congrats on the weight loss!! Do what you have to do to get it done...

But...

I too spent much of my life dealing with obesity, and I'm T2 (which is the condition these meds were designed for) - personally, I won't take these medicines.

At the end of the day, for this to be sustainable and healthy - are lifestyle changes are required, for our entire lifespan.

If the meds help jump start the process - great. But everyone needs to plan for life post meds. If not, they will go back to the exact same place, or worse.
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Old 08-24-23, 09:33 AM
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Originally Posted by Grudey1
Started 290 lbs. back in early February. The clinic that I go to has a InBody body composition scanner that I can use any time I want to. It shows (with a printout of metrics) that I am losing fat and gaining muscle. I lost 5 inches off of my waist. Now... I have made serious lifestyle changes. I vigorously lift weights 4 to 5 hours per week and ride 3 to 5 hours per week. I prioritize protein in every meal, take supplements to include "green powders' such as AG1 and make a conscious effort to get enough sleep. I get my Semaglutide from a compounding pharmacy and thus do not pay the exorbitant prices for the name brand Wegovy.

Haters gonna hate but I am willing to stay on some level of Semaglutide for the rest of my life if I have to. It has given me a fighting chance to get my health back. Anyone who doesn't understand this has never spent most of their life contending with obesity.

we started at around the same time it seems. My start weight was 324. I completely agree with your last sentence.

i have stalled out on weight loss since my last update to the thread, But I will work it out.
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Old 08-25-23, 11:18 AM
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Originally Posted by Calsun
Studies have found that people do lose a lot of weight with the semaglutide drugs but regain it in a few months if they stop taking the drug. At $12,000 a year for life I do not see this as a viable solution for most people. I understand the desire to have a pill or a shot and no expend wny effort and lose weight but it is by far the most expensive route to take.

The alternative is prolonged exercise which is not possible for some individuals. For those who can exercise they are going to get more long term benefits from doing so.
I came to this thread to learn if I might want to try ozempic, this comment gave me the information I needed to know this is not for me.

Interested in learning from all of your stories though! I hope all of you get to the bodies that will enable to you to get the most out of life!!
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Old 08-25-23, 11:24 AM
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Originally Posted by monogodo
About 7 years ago I was on the Naturally Slim program. It mainly taught good eating habits - portion control, eating slowly, only eating when hungry, etc. I lost quite a bit of weight on it.
I went through that program via work about 5 years ago, similar impression. It's good advice, but I unlearned it pretty quickly. I got down to 225 I think, but now i'm back up at 250 where my lifestyle seems to always converge to. I ride to work 11mi round trip when I can (2 days a week during the school year, more during the summer), ride trails on the weekend, and have been a non-breakfast person since well before Naturally Slim (black coffee until lunch around 11-12). My problem is that lunch opens the floodgates. I snack all day (too many free food opportunities at work), eat seconds at dinner when I don't need to (wife is a good cook), and keep snacking after dinner.

#1 lesson from Naturally Slim, if I could live by it, I'd be in good shape: don't eat until you're actually hungry.

#2, which is kind of the same rule: if it's mealtime and you're not actually hungry yet, you ate too much at your last meal.

#3 when you're extra hungry, that doesn't mean you have to (get to!) eat extra much to get to regular full.
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