I have a 3T Team Dorico seat post on my Cervelo and I have been having some trouble with it. I finally got the seat adjusted properly and now I cant keep it tight. The two screws that hold the seat in place keep coming loose and the seat moves. Even if I tighten the hell out of them they still come loose about 20 miles into my ride. Has anyone else had this issue and what should I do to help this issue?

I have the same issue, although not as severe as you are describing. I think the top clamps may be too small to support the rails properly for heavier riders (I am 225 lbs).

That may be the case. Never thought of that.

Not here, it works perfect for me. ~160lb rider.

Have you tried using some fresh blue loctite. If that isn't enough then some red loctite should keep them at proper torque. Do you know the torqu specs for them and have a torque wrench?

I have the issue and I'm about 170 (I think).

I guess I will try the Loctite! I am unsure of the torque specs in the seat bolts but I am very careful to torque the post properly!