We're a 350 lb team running the 4 Seasons on 28mm rims: 120 psi rear, 115 psi front. Haven't had a single pinch flat. I'm guessing we'll get 1500 miles out of the rear tire, more out of the front of course. Around where we ride I don't know that a thicker tube would help. Nothing stop's a goat head and when they mow next to the shoulder those little, suckers are all over the place. We haven't had a single rear flat since the first rain of the year. I was concerned about even the 28mm, but Todd at daVinci said we'd be fine if we kept the pressure up: he was right. I started with Gatorskins, but switch to the 4 Seasons when I started carrying a folding tire on longer rides; I know carrying a spare tire is overkill, but I actually used it when I got a piece of glass in a tire that I couldn't remove. And the 4 Seasons are so easy to get on/off.