I suggest following the tried and true advice: Get a Brooks saddle (B17 or Champion Flyer); some padded, Spandex bike shorts (or bibs); get off your bike every hour, if only for 5 minutes; take a rest day every week, or more often if need be.

See if any or all of those remedies help. My feeling is that Brooks saddles may not work for everyone, but anyone with sore butt troubles should at least give one a try - so many of us swear by them (including me.) Get it from Wallbike and you can return it if it doesn't work for you.

I had sore butt problems much worse on my motorcycle. However, I discovered that if I got off it, even briefly, my butt seemed to "recharge" and I was good for another hour or so. On long trips I'd stop for gas, food, to go to the bathroom, to take a picture....just about anything. When I got back on I felt better. The relieving effect didn't seem to diminish over the course of a day.

My Brooks saddle is the best I've found, but after many long days my butt starts to get uncomfortable. Rest stops help a lot, but a rest day is even better, and my whole body (and soul) appreciates it, not just my butt.

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DISCLAIMER: I admit, I didn't read all the posts before I added my two cents. If I've repeated anything, I apologize. I'm in a hurry. I should be getting ready for work!