i do have three different wheelssets. two ****ty bomb proof wheels that often are more flexible then jello, and i have a set of reynold strikes that i use for races/occation training days (like the day before a tri to get used to the affect of winds on them.) different tires? yes but not because i care more just because i have alot of tires. they all are 23's and they all work just fine. it really depends if your new wheels are "nice" ($700+) then do not use them ever day theres no point why risk breaking something nice. if there $200 dollar bombproof wheels it all depends. if they're alot nicer than your og wheels then use them everyday. if they're only a little bit nicer dont bother using them except for race.