When I was touring in South America I used the MKS Touring Lite platform pedals with regular running shoes. They were fantastic because in SA I was doing a lot of touring on and off the bike checking out all the sites. Cycling with platform pedals meant I only had to carry one pair of shoes. I also didn't feel I was missing out on the efficiency of being clipped in because a lot of the roads were very loose gravel roads and there was no way I'd want to be clipped in.

When I flew up to Canada from SA to do my cross Canada ride I knew I'd be on pavement the entire time so swapped out to clipless pedals and loved them. They're so much nicer to ride in and you feel so much more powerful and can spin faster and pretty much do everything better. At the start I carried my cycling shoes and off bike shoes but in Canada I found I was not doing any off bike site seeing so sent the off bike shoes home. No regrets.