Originally Posted by
Shimagnolo
The fact you are going from a knobby tire to a smooth one will make the largest difference.
+1
The weight difference probably makes a minimal difference, but those are very different tires.
Originally Posted by
woodway
You will notice a huge difference in speed. You will also notice a huge difference in ride quality (it will get rougher).
This is somewhat true, but I wouldn't give it unqualified agreement. The small block tires do absorb more irregularities in road surfaces, but on decent pavement I much prefer the way a slick tire feels. YMMV