+1 for Psimet. If you contact him, please be specific about your weight, expected riding conditions, and whether you're Shimano/SRAM or Campy.

Even if you don't expect to ride aggressively, climbing will have you stressing the rear wheel. You might want to ask about a 32 holes front and 36 holes rear combo. Rob (Psimet) tends to be conservative, which IMO is exactly what will serve you best.