I've used Andiamos and one or two other brands over the years. Because of the thinner pad, they're not as comfortable on the bike, but they're more comfortable off the bike. I would wear them when I was going to ride somewhere and be hanging out for a while, and didn't want to change.

The downside was that they cost almost as much as off-brand bike shorts, and they wore out a lot faster. So these days I just wear regular underwear or bike shorts under my clothes, depending on the length of the ride and the weather.