I've heard of people having some trouble with american classic hubs. Not those in particular, but i'd check out some reveiws/talk to some people before lacing them up.

+2 cents. lace it up with some decent sturdy spoke nipples, especially if you ride hard/in inclimate weather. I've went to true wheels before and just had the nipples turn to dust. The weight you'd save just isnt worth it I don't think. Most people tend to bypass nipples and spokes as sort of just there, when merely having an experienced wheel builder lace a wheel up with some quality spokes can drastically change the way a wheel perfrorms. Also if you are inexperienced with wheel building, it is pretty difficult to do very well and having a "professional" do it may be well worth it. Id poke around and see if there are any shops that do any low key celeb bikes or if there are any mechanics around that do wheel builds for higher profile riders, that would be your go to man, as they would know more about certain products and how they perform under tougher riding, as well as how they hold up in the long run. A good mechanic that you trust is well worth paying him for his service I think, and once you develop a relationship most mechanics will help you out as much as they can.

good luck with everything!
hope this post helps in some way.