If it's just minor nose congestion, I'd say go for it, but take it easy. If you have any other symptoms like fever, chills, muscle aches, nausea, headache, cough, or wheezing, then I'd say get a big bowl of chicken soup and a blanket. Remember that most cold medicines don't cure anything, they just mask symptoms. The exception may be, controversially, zinc based preperations that have some evidence showing that they actually mess with the replication of the cold virus and thus may shorten the duration of infection. Ask your doctor or pharmacist if you are considering medication that you aren't familiar with.