I've heard of people throwing their saddle in the oven at ~200 or so for a short while before hitting it with proofide so as to open up the pores (well it probably doesn't have functional pores anymore now that it's dead, right?) or whatever in the leather and also so the proofide is nice and runny and seeps in really well.
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Bikes: 1996 Eddy Merckx Titanium EX, 1989/90 Colnago Super(issimo?) Piu(?), 1990 Concorde Aquila(hit by car while riding), others in build queue "when I get the time"