Bigger charinring = smaller cog (rear) = go more distance per pedal revolution = go faster = more force on the pedals.
Smaller chainring = bigger cog (rear) = go less distance per pedal revolution = go slower = less force on the pedals.

But that's not all you asked. Is that difference significant? Not really. Those ratios are comparable to about 51 and 55 gear-inches on a bike with the more common 700c wheels. That difference is about "one click's worth" on a modern zillion-speed indexed system. You can feel the difference if you are trying to maintain an optimum cadence riding for speed, but otherwise it won't matter one bit. If you are changing your gearing because you are changing your riding style, then you need to reconsider.