At 145 lbs, I'd venture to say the OP could run 16/20 with the H Plus Son rims if he can find a good wheelbuilder.

But dang those are heavy. I'm over 200 lbs and I use 32h DT Swiss RR585s on the rear wheels I ride for training (and yes, I can FEEL the weight difference) and I thought those were boat anchors. The H Plus Son's are battleship anchors.

As a pure fashion statement, great. They do look wonderful.

But day-um, at 42 mm they're not even really all that aero. At 145 lbs, just get something like this if you want aero:

http://www.novemberbicycles.com/rfsc-58s/

And this if you don't:

http://www.novemberbicycles.com/fsw-23/