As others said, folding tires are generally better quality so they would tend to ride better then wire beads. The main difference, however, is that folders are lighter weight. The lighter weight of folders is a big advantage if you are riding on hilly terrain or need to carry a spare tire -- such as while bike touring. I use folding tires on all of my bikes because it is very hilly where I ride and I need all the help I can get climbing.