I did the North Florida MS 150 ride last September, St augustine to Daytona Beach. Great Ride and the Support was great. The best Organized Ride I have ever done.
If you can do consistent 50 mile rides 2 or 3 times a week it will not be a problem for you.

Grendel . I rode for Team HP one day and Cody's challenge the Next day. That way I was able to support 2 teams.